I dont know what your budget is and if the camping part is something you really want to do but if it were me and this was my first long distance trip, I would pick a point about halfway, between Medford and Redding somewhere and go to one of the websites like priceline.com and type in $25 and see if you get any takers. I wouldn't carry a tent, sleeping bag, and all the other camping necessities for one night. I don't have to tell you the road between PDX and SFO is pretty demanding and heavily traveled and being wide awake and alert is a must, in my opinion. This is a pretty easy two day trip and a good one for your first but I bet you are still going to be tired after 300-350 miles on those curving, twisty, hilly roads. Get a good night's sleep, take a shower in the morning and be wide awake and safe.
This is what I am doing next month on my Chicago to Phoenix trip, four 400+ mile days in a row.
Just my opinion, ymmv (your mileage may vary)