Could be a lot of causes, hot spots in cylinder or head, air/fuel mixture, low octane fuel, vacuum advance. The easiest first test is to remove the vacuum line from the #3 carb that goes to the vacuum advance on the rear of the engine. Cap off the carb vacuum port and plug up the vacuum line and test it, see if the noise goes away. If the noise is gone then the vacuum advance diaphragm is probably leaking or the ignition advance plates or stuck.